Modified Release dosage forms offer definite advantages over conventional Release formulation of the same drug.
The Three-Layered matrix system overcomes inherent disadvantages of non-linearity associated with the core, covered by two additional layers, each with different rates of swelling, gelling and erosion, is what accounts for the rate of drug release.
As time goes by and the core swells, th.
When the Tablet is first swallowed, the drug concentration is high but the surface area is small.
Modified Release dosage forms offer definite advantages over conventional Release formulation of the same drug.
The Three-Layered matrix system overcomes inherent disadvantages of non-linearity associated with the core, covered by two additional layers, each with different rates of swelling, gelling and erosion, is what accounts for the rate of drug release
