The stability of the DNA Double Helix is contingent on fine-tuning a number of physicochemical control parameters. thermal and mechanical dissociation, force-induced melting, equilibria of hairpin-li.
The present book aims at providing a self-contained account of the Statistical Physics of cooperative processes in DNA, e.g.
Varying any one of them leads to separation of the two strands, in what constitutes a rare physical example of a thermodynamic phase transition in a one-dimensional system.
The stability of the DNA Double Helix is contingent on fine-tuning a number of physicochemical control parameters