Hyperuricemic is a condition of the increase of uric acid content in body that can cause inflammation, particularly on joints, and has a positive correlation with several degenerative diseases, such as kidney disease, increase of triglycerides amount, obesity, and insulin resistance, heart disease, and hypertension.
One of food product.
Therefore, study is done in form of functional beverage which is considered to be more practical and natural.
This is considered unpractical to be applied on food products.
According to Sutomo, flavonoid compounds could reduce uric acid content by inhibiting xanthine oxidase enzyme.
Study of anti uric acid activity from Soursop leaves is mostly in form of extract form certain solvents.
Soursop leaves ability to lower uric acid is probably because of flavonoid content in Soursop leaves.
Reported that butanolic extract of Soursop leaves could reduce uric acid content better than allopurinol on wistar rats.
Xanthine oxidase enzyme catalyzes reaction of hypoxanthine into xanthine and then oxidized into uric acid.
A potency of Soursop leaves as antihyperuricemic has been reported, in vitro Using xanthine oxidase enzyme, as well as in vivo Using rats.
Multifunction properties from Soursop leaves extract are related to their active compounds, such as flavonoid, tannins, calcium oxalate, alkaloids, fatty acids, phytosterols and myricyl alcohols.
Soursop leaves have been reported to have anti uric acid activity, anti inflammation, antinociceptive and antiulcerogenic, anticancer, antidiabetic, anticholesterol, and antioxidant.
A part of Soursop plant that has been reported to contain active compounds is its leaves.
One of plants that contain many active compounds are Soursop that flourishes in Indonesia.
Natural ingredients that contain active compounds which give pharmacological effects are secondary metabolites from plants.
Therefore, people started Using traditional treatment which uses natural ingredients, because it is considered safer and more economic.
Medicine consumption often causes Side effects and it is more expensive.
Several ways can be done to reduce or prevent uric acid disease, such as by managing the eating pattern and/or consuming anti uric acid medicine.
Uric acid problem occurs mainly because of unhealthy eating pattern, which are over-eating pattern and high consumption of foods that contain high uric acid.
Reported that hyperuricemic condition could increase the risk of degenerative diseases 1.6 times higher.
Hyperuricemic is a condition of the increase of uric acid content in body that can cause inflammation, particularly on joints, and has a positive correlation with several degenerative diseases, such as kidney disease, increase of triglycerides amount, obesity, and insulin resistance, heart disease, and hypertension
