The book reproduces 55 of more than 300 articles written by the author, representing milestones in methods development of Single-Particle cryo-EM as well as important results obtained by this technique in the study of biological macromolecules and their interactions.
Although the biological applications are mainly in the area of ribosome structure an.
Importantly, neither symmetries nor ordered arrangements (as in two-dimensional crystals, helical assemblies, icosahedral viruses) are required.
The book reproduces 55 of more than 300 articles written by the author, representing milestones in methods development of Single-Particle cryo-EM as well as important results obtained by this technique in the study of biological macromolecules and their interactions